West Lafayette is a city in Wabash Township, Tippecanoe County, Indiana, United States, about 65 miles northwest of the state capital of Indianapolis and 103 miles southeast of Chicago. West Lafayette is directly across the Wabash River from its sister city, Lafayette. As of the 2016 census estimate, its population was 45,872. It is the most densely populated city in Indiana and is home to Purdue University.